let’s start off with a little history. working with my psychiatrist, we added bupropion, generic wellbrutin, to my lithium. at 300 mg, I saw no effect. then the dose got bumped to 600 mg; i saw effects, side effects, that is. keep in mind by hand normally tremor, but at the higher dose the tremor doubled. i think there were other side effects, but I can not remember. so, we made the decision to cut back to 300 mg.