since I started taking bupropion, i’ve always taken a multiple of 150 mg tablets. here’s a quick rundown.
- started at 150 mg
- moved to 300 mg
- tried 600 mg- side effects that I don’t recall
- back to 300 mg
- tried 450 mg– good results but i couldn’t stand the constant headaches and ear ringing.
- back to 300 mg.
i’ve never really felt a discernible difference with bupropion, but at least there weren’t any noticeable side effects at the 300 mg dosage.
- fast forward to about a week ago- i felt like i had some depression slippage going on.
- fast forward to three days ago- i had a headache that wouldn’t go away. I just attributed it to something going on that would go away. it hasn’t.
- fast forward to last night- i noticed i had ringing in my ears.
have headache & ear ringing happened before? well, yes it has when i tried 450 mg of bupropion. suddenly it appears i am having a side effects at a 300 mg dosage witch the bupropion that I never experienced before.
the next question would be, “well, has anything changed?” the answer would be no – but – yes. i know that sounds confusing. let me explain.
last time i got my script filled, i got 300 mg tablets instead of 150 mg. 2- 150 mg tablets would equal 1- 300 mg tablet, no biggie. or so you thing.
i started taking the 300 mg tablets 11 days ago. i know, i counted. 19 pills left from the 30 I got. (i know it may be tough math, but stick with me. I’m pretty sure 30-19 is 11. feel free to check my work.) since then, I have felt slightly more depressed, had continual headaches kick in, and ear ringing that won’t stop. sounds like side effects to me. so, something is going on, i don’t know what.
i will talk to my pharmacist today. thankfully, i still have a few of the 150’s around. part of me hopes the manufacturer changed. since they are generic and this is treating a mood imbalance that might not be the best thing. i’ve heard sometimes a switch in generics are enough to through things off. it also could be my math is off and 150 + 150 does not equal 300. guess i’ll find out tonight and report my findings to you.
signing off for now with headaches, ear ringing and a slightly depress mood.
facing off with the big d 
I’m sorry you’re having those side effects! I hope your symptoms subside soon and you get on the right dosage soon. I constantly battle trying to balance my synthroid dosage and my glucose levels- I know those side effects suck and add fatigue and frustration and depression and that’s a cocktail of trouble. Wishing and hoping the best for you!
actually, I was stable at 2×150. the switch to 1×300 rocked my stability even though they were the same formulation. yea, right!
Ugh sorry they are doing that. I forget which drug it was, but when my pharmacy switched to giving me the higher dosage tablet over two that equalled that dosage, I felt very off as well.
damn insurance companies. they want to save a few bucks, paying for few pills because, “they are identical formulations”. i wish they’d get clue, or at least, buy a vowel.
With yours, was your one big pill even the same size as two regulars combined? With Zoloft I think, I went from two small pills to a huge horse pill that was probably four times as big. I would imagine that whatever extra was in that would impact how my body breaks it down in some way.
thankfully, my 300mg pill was only about twice the size as the 150mg. I didn’t have to neigh. (sorry, i had to go there) (-:
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